Process for case study:
Personalized Cancer Medicine
Process for case study:
Personalized Cancer Medicine
3D Bioprinting Process
3D Bioprinting Process
1. IMAGE ACQUISITION
- Image the organ or tissue to be bioprinted (e.g., with magnetic resonance imaging (MRI), computed tomography (CT), X-ray, or ultrasound)
- Obtain ready-to-print sample models of organs and tissues from the National Institutes of Health (NIH) repository: https://3dprint.nih.gov/
1. IMAGE ACQUISITION
- Image the organ or tissue to be bioprinted (e.g., with magnetic resonance imaging (MRI), computed tomography (CT), X-ray, or ultrasound)
- Obtain ready-to-print sample models of organs and tissues from the National Institutes of Health (NIH) repository: https://3dprint.nih.gov/
2. IMAGE PROCESSING
- Segment image raw data using image-processing software.
- Create a 3D CAD surface model in .STL format from image segmentation. This surface model approximates the outer shape of the construct using triangle mesh.
- The surface model is then filled with repeating unit cells to generate the complete construct with internal infrastructure.
- Brinter™ software generates a toolpath plan as a g-code file from the 3D model. This provides the motion path for the bioprinter to deposit bioink at the proper time and location.
2. IMAGE PROCESSING
- Segment image raw data using image-processing software.
- Create a 3D CAD surface model in .STL format from image segmentation. This surface model approximates the outer shape of the construct using triangle mesh.
- The surface model is then filled with repeating unit cells to generate the complete construct with internal infrastructure.
- Brinter™ software generates a toolpath plan as a g-code file from the 3D model. This provides the motion path for the bioprinter to deposit bioink at the proper time and location.
3. 3D BIOPRINTING
- A cell-laden hydrogel solution is prepared by mixing cells with the chosen hydrogel solution.
- Prepared bioink is loaded into the Brinter™ bioprinter.
- Surface model (g-code file) is read into Duet3D software controlling the printing process.
- 3D bioprinter builds the tissue model layer-by-layer.
- Cell-laden construct can be chemically or physically cross-linked after printing for structural integrity.
3. 3D BIOPRINTING
- A cell-laden hydrogel solution is prepared by mixing cells with the chosen hydrogel solution.
- Prepared bioink is loaded into the Brinter™ bioprinter.
- Surface model (g-code file) is read into Duet3D software controlling the printing process.
- 3D bioprinter builds the tissue model layer-by-layer.
- Cell-laden construct can be chemically or physically cross-linked after printing for structural integrity.
Our vision is to improve worldwide health and save lives by advancing bioprinting technology and increasing its applicable uses.
Our vision is to improve worldwide health and save lives by advancing bioprinting technology and increasing its applicable uses.
Our vision is to improve worldwide health and save lives by advancing bioprinting technology and increasing its applicable uses.
Our vision is to improve worldwide health and save lives by advancing bioprinting technology and increasing its applicable uses.
Latest Publications
Follow Brinter research and publications.
Brinter Raises €1.2M in Seed Funding to Accelerate 3D Printing Bioscience Research and Manufacturing for Uses That Range from Personalized Drugs to Human Spare PartsBrinter Raises €1.2M in Seed Funding to Accelerate 3D Printing Bioscience Research and Manufacturing for Uses That Range from Personalized Drugs to Human Spare Parts
Brinter Raises €1.2M in Seed Funding to Accelerate 3D Printing Bioscience Research and Manufacturing for Uses That Range from Personalized Drugs to Human Spare Parts
Turku, Finland (June 10th, 2021) Brinter announces the successful closure of a €1.2M seed funding round led by early-stage VC [...]
Brinter Team Member Contributes to Scientific Cancer Research
Brinter's scienfic developer, Antti Arjonen, (PhD, Cell/Cellular and Molecular Biology) contributes to ovarian cancer research. The scientific article was published [...]
5.5 million for a Project on Smart Matrices for Knee Cartilage Repair
A research project in cartilage regeneration and cartilage repair, in which Brinter (3DTech) participates together with nine other partners [...]
